Ghanaian researcher Nana Kwame Kwabi Boateng has played a key role in an international study that is reshaping the scientific understanding of how bl
Ghanaian researcher Nana Kwame Kwabi Boateng has played a key role in an international study that is reshaping the scientific understanding of how blood clots form.
Boateng, the first author of the study published in Blood, the world’s leading hematology journal, helped uncover the role of a previously overlooked enzyme in clot formation.
Blood clots rely on the protein fibrin, which forms a mesh-like network to stop bleeding when a blood vessel is injured. This network is typically stabilized by the enzyme Factor XIII. The new research, however, reveals that tissue transglutaminase (TG2) can modify a specific part of fibrin called the β-chain during traumatic injury—a component previously thought to play little role in clot formation.
This discovery offers fresh insights into the structure and function of blood clots, with potential implications for trauma care, wound healing, and the treatment of clotting disorders.
The study was conducted in collaboration with scientists from Denver Health Medical Center, Rutgers University, Michigan State University, and the University of Colorado. It was co-led by Prof. Kirk C. Hansen of the University of Colorado and Prof. James P. Luyendyk of Michigan State University.
Nana Boateng, a registered pharmacist and graduate of Central University’s School of Pharmacy, holds a Master of Science in Clinical Pharmacology (with Distinction) from the University of Aberdeen, UK, and is currently pursuing a PhD at Michigan State University.
The discovery has been highlighted by the Michigan State University College of Veterinary Medicine for its potential to transform the understanding, diagnosis, and treatment of trauma, wound healing, and clot-related conditions in both humans and animals.
In recognition of his work, Boateng was invited to deliver an oral presentation at the 2025 Joint Conference of the International Fibrinogen Research Society and the International Society for Fibrinolysis and Proteolysis in Greece, where he received a research award for his presentation.
This announcement is distributed by Africa Publicity on behalf of Nana Kwame Kwabi Boateng.